Smooth pursuit and saccadic abnormalities in first-episode schizophrenia

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Smooth pursuit and saccadic abnormalities in first-episode schizophrenia.

BACKGROUND Previous studies of oculomotor dysfunction in schizophrenia have tended to concentrate on abnormalities of smooth pursuit eye tracking in chronic medicated patients. We report the results of a study of smooth pursuit, reflexive and antisaccade performance in drug naive and antipsychotic treated first-episode schizophrenic patients. METHODS Smooth pursuit and saccadic eye movements ...

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BACKGROUND Grey matter and other structural brain abnormalities are consistently reported in first-onset schizophrenia, but less is known about the extent of neuroanatomical changes in first-onset affective psychosis. AIMS To determine which brain abnormalities are specific to (a) schizophrenia and (b) affective psychosis. METHOD We obtained dual-echo (proton density/T2-weighted) magnetic r...

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Saccadic and smooth-pursuit eye movement in neurootological diagnostic procedures.

The origin of the generation of saccadic and smooth-pursuit eye movements has not been proved. The goal of the study reported here was to search for the connection of visuooculomotor reactions--saccades and eye-tracking test--with cerebellar damage. Using electronystagmography, we tested 11 patients treated with aminoglycosides because of pneumonia. After a mean of 21 days of pharmacological th...

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ژورنال

عنوان ژورنال: Psychological Medicine

سال: 1998

ISSN: 0033-2917,1469-8978

DOI: 10.1017/s0033291798006722